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SAN DIEGO, May 20, 2021 (GLOBE NEWSWIRE) — via InvestorWire — Green Hygienics Holdings Inc. (OTCQB: GRYN) (“Green Hygienics” or the “Company”) is pleased to announce it has entered into a scientific research collaboration agreement with Cinvestav, the Center for Research and Advanced Studies of the National Polytechnic Institute (Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional).

The institute, a high-ranked leading Mexican multidisciplinary scientific research institution, will work with Green Hygienics to advance its R&D efforts through the characterization and development of cannabinoid-based products targeting endocannabinoid system (ECS) deficiencies in animals and humans. Cinvestav ranks fourth among research centers in Latin America and ranks 118th in the world.

Dr. Luisa Lilia Rocha Arrieta, Ph.D. M.D., and Kyle MacKinnon, COO Green Hygienics Holdings Inc.



Dr. Luisa Lilia Rocha Arrieta, Ph.D., M.D., a top research investigator at the Department of Pharmacology at Cinvestav, said, “The treatment of chronic pain has relied heavily on opioids, despite their potential for addiction, overdose and the fact that they often don’t work well when used on a long-term basis. There’s an urgent need for more effective and safer options. These new collaborative research projects, like we’ve established with Green Hygienics, will investigate substances derived from hemp that don’t have psychoactive disadvantages, looking at their basic biological activity and their potential mechanisms of action as endocannabinoid system (ECS) modulators.”

“This research collaboration will be our first project under TruLife Biotech LLC, a Green Hygienics Company focused on the development and advancement of innovative cannabinoid-based nutraceutical and skincare products and brands,” stated Dr. Levan Darjania, chief scientific officer of Green Hygienics. “The collaboration with Cinvestav will augment ongoing efforts by both parties to identify and explore selected cannabinoids and terpenes in planned combinations that may act synergistically to protect against pain development and determine their potential efficacy as pain relievers against inflammatory and neuropathic pain. Therefore, the Company is building its collaborative model with academic institutions and will utilize its TruLife Biotech R&D platform to create proprietary and highly efficacious cannabinoid-based products.”

“Discovery and development of cannabinoid-based products that are truly effective in producing a desired result are global tasks that are based on multidisciplinary approaches, collaborations and partnerships. After meeting with leading researchers at Cinvestav’s Mexico City Campus, we are confident in our collaboration on the development of new and efficacious products,” stated Kyle MacKinnon, COO of Green Hygienics. “Offering researched-backed products that actually work for their intended purpose will lead us to stay ahead of the curve of regulatory approval, allow our products to stand apart from the competition, and is the fastest and most cost-efficient way to expand into new markets,” MacKinnon concluded.

About Cinvestav

The Center for Research and Advanced Studies of the National Polytechnic Institute (Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional) is a Mexican scientific research institution affiliated with the National Polytechnic Institute and founded by President Adolfo López Mateos on April 17, 1961. The institute is divided into 10 research centers; 3 of these are in Mexico City, while the others are dispersed across the country. The institute is divided into 33 departments focused on natural sciences, biological sciences and health, technology and engineering sciences, and social sciences and humanities.

For more information on the Cinvestav Pharmacology department please visit

https://www.cinvestav.mx/Departamentos/Farmacologia.



About Green Hygienics Holdings

Green Hygienic Holdings Inc. (OTCQB: GRYN) (“Green Hygienics” or the “Company”) is a California-based innovative, technology-driven enterprise focused on the high standard cultivation and processing of industrial hemp and manufacturing of pharmaceutical-grade bioactive cannabinoids. The Company’s corporate mission is to adhere to the highest standards of operations in consistently delivering safe and premium-quality products to consumers as well as to partner with CPG (consumer packaged goods) and pharmaceutical companies.

Hygienics is the science of preserving and promoting the health of individuals, communities and the planet.

For further information about Green Hygienics Holdings Inc., please visit the Company’s website at: www.greenhygienics.com

Follow us on:

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Corporate Communications:
Heidi Thomasen
IR@GreenHygienics.com
Toll Free 1.855.802.0299

CAUTIONARY STATEMENT CONCERNING FORWARD-LOOKING STATEMENTSThis document contains forward-looking statements.  In evaluating these forward-looking statements, you should consider various factors, including our ability to change the direction of the Company; our ability to keep pace with new technology and changing market needs; and the competitive environment of our business. These and other factors may cause our actual results to differ materially from any forward-looking statement.

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https://www.investorwire.com/press-releases/green-hygienics-holdings-inc-gryn-executes-agreement-with-cinvestav-the-leading-mexican-academic-research-institution-to-advance-research-targeting-endocannabinoid-system-ecs-deficiencies/

  • Even major players in the CBD market do not offer detailed and verifiable study results to effectively differentiate their products on the basis of meaningful clinical findings, essentially exploiting the “natural” label without any R&D efforts

  • This industry deficiency represents immense opportunities for R&D-driven companies such as Green Hygienics

  • Green Hygienics intends to use its intellectual and capital resources to establish and apply state-of-the-art research and development to a new generation of cannabinoid-based products having specifically assessed health-wellness efficacies


CBD Reality Check 

Interest in the therapeutic use of hemp-derived nonintoxicating cannabinoids, such as cannabidiol (“CBD”) and cannabigerol (“CBG”), has reached a fever-pitch in recent years followed by the early-stage preclinical discoveries surrounding the tentative functional role of the endocannabinoid system (“ECS”). CBD received a further popular validation since U.S. FDA approved Epidiolex(R) as adjunctive therapy for pediatric patients with drug-resistant epilepsy.

During the last 5-8 years, CBD has been highly acclaimed and heavily hyped. Its medicinal qualities are perceived as limitless by some, and its non-psychoactive nature makes it “suitable” for just about anyone, as it has been claimed by many activists and business entities. The broad-ranging claims of CBD therapeutic utilities are endless, while monopolistic entrepreneurs are rushing the industry in droves, touting first-to-market achievements over quality, research-backed product offerings.

Current Status-Quo and Future Expectations 

A case can be made that the majority of CBD companies simply ignore the lack of efficacy in their products to avoid potentially undermining their commercial utility, preferring to exploit the “natural” label without any R&D efforts, the very efforts that could establish important evidence-based credibility for their products. Companies marketing products containing CBD have been over-exuberant in their claims about its effectiveness. They have been guilty of illegal, sleight-of-hand, exploiting public enthusiasm over cannabis/hemp by portraying all cannabinoids as not only safe but capable of ameliorating the symptoms of many serious medical conditions.

Consequently, the reputation of CBD as a universal “cure-all” puts this still promising substance in the same class as other “natural” panaceas, where anecdotal cases and overwhelmingly biased testimonials supersede the proper efficacy evaluation of already marketed CBD finished products.

Notwithstanding, while CBD and other hemp-derived cannabinoids remain a formally unproven therapeutic option with a known mechanism of action, physicians and holistic health/wellness practitioners remain open to the possible future role of these products in the field of alternative management and prophylaxis of different health conditions such as chronic inflammation and pain. Emerging companies like Green Hygienics Holdings (OTCQB: GRYN) have an opportunity to paint a brighter future for the CBD industry and provide a research-based platform for which these physicians and holistic health/wellness practitioners can specifically select and recommend beneficial products meaningful to their intended purpose of providing patient relief.

To recommend a particular cannabinoid-based product to patients and wellness-oriented end-users, those practitioners need to adequately analyze specific information and study reports on the experimentally assessed systemic exposure, bioavailability and targeted efficacy of a particular product, instead of focusing solely on the certificate of analysis (“COA”) that verifies only the concentration of bio-active ingredients and absence of harmful contaminants.

A very brief survey gathered from the published scientific and commercial papers or conference presentations indicates that even the major players in the CBD market do not possess such study results and reports to differentiate and promote their products based on at least preclinical and/or exploratory clinical study findings.

Green Hygienics is Poised to Address the Current State of the Industry

On the other hand, this particular status-quo represents the immense opportunities for R&D-driven companies like Green Hygienics in an everchanging cannabinoid market landscape. Physicians and holistic health/wellness practitioners are looking for more advanced, evidence-based cannabinoid products with high, unparalleled, and most importantly unbiased therapeutic efficacies of achievable health-beneficial effects. Green Hygienics is an enterprise that has developed a model resting on this exact premise of bringing evidence-based cannabinoid products to market, backed with unbiased therapeutic efficacies, through research-based evidence.

The company aims to be a leader in compliance and capabilities in the hemp and cannabinoid supply marketplace. By leveraging state-of-the-art technologies, the company intends to open up a whole new world of fully characterized novel cannabinoids and targeted bio-delivery technologies never before explored.

Green Hygienics is aimed at maximizing the use of intellectual and capital resources. Therefore, the Company has decided to move forward with the establishment of a state-of-art biotechnology R&D facility to focus its resources on the rational and innovative design of formulations, development and experimental evaluation of the new generation cannabinoid-based products with superior bioavailability and specifically assessed health-wellness efficacies.

Discovery and development of highly efficacious cannabinoid-based products is a global task that is based on multidisciplinary approaches, collaborations, and partnerships. Therefore, Green Hygienics is building its collaborative platform with several academic institutions, both domestically and abroad, to utilize well-established endocannabinoid system (“ECS”) target screening models and develop customized wellness products addressing ECS deficiencies. The ultimate goal is to develop and promote highly functional, experimentally assessed and supported efficacious nutraceutical products that will be trusted by medical communities, physicians, holistic health practitioners, and wellness-oriented end users.

For a more in-depth exploration on this topic, please refer to this paper published in Nutritional Outlook by Levan Darjania, PhD. (https://cnw.fm/svoTE).

About Green Hygienics Holdings

Green Hygienics Holdings Inc. (OTCQB: GRYN) is a California-based innovative, technology-driven enterprise focused on the high standard cultivation and processing of industrial hemp and manufacturing of pharmaceutical-grade bioactive cannabinoids.

The company’s corporate mission is to adhere to the highest standards of operations in consistently delivering safe and premium-quality products to consumers as well as to partner with CPG (consumer packaged goods) and pharmaceutical companies.

The company intends to be a leader in compliances and capabilities in the hemp and cannabinoid supply marketplace. Using state-of-the-art technologies, Green Hygienics intends to open a whole new world of novel cannabinoids and targeted bio-delivery technologies never before explored, solving the issues of stability, pharmacokinetics, biological tissue penetration and bioavailability.

GRYN is building a team of visionary agrotechnology, pharmaceutical and life scientists working at the intersection of nutraceutical, cosmeceutical and pharmaceutical technologies with a goal to improve lives.

View GRYN’s corporate video and follow the company on Facebook, Twitter and Linkedin.

Corporate Communications:
Heidi Thomasen
IR@GreenHygienics.com
Toll-Free 1.855.802.0299

For more information, visit the company’s website at www.GreenHygienics.com.

NOTE TO INVESTORS: The latest news and updates relating to GRYN are available in the company’s newsroom at http://cnw.fm/GRYN 

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SAN DIEGO, May 04, 2021 (GLOBE NEWSWIRE) -- via InvestorWire – Green Hygienics Holdings Inc. (OTCQB: GRYN) ("Green Hygienics" or the "Company"), announces today that it will move forward with the establishment of TruLife Biotech, LLC., to focus on the development and advancement of innovative cannabinoid-based nutraceuticals, skincare products and wellness brands addressing endocannabinoid system (ECS) deficiencies in humans.

“The interaction of hemp-derived cannabinoids with ECS has been rigorously studied for the last 20 years. There’s an awful lot of preclinical data available, and the question is how much is genuine, and practically useful, as far as efficacious, new nutraceutical and wellness product development is concerned. In order to recommend a particular cannabinoid-based product to wellness-oriented end users and practitioners, product developers need to follow the rational product design and development path and support their products and brands with specific information such as safety, stability, experimentally assessed bioavailability and targeted efficacy of a given product,” stated Dr. Levan Darjania, Chief Scientific Officer of Green Hygienics and co-founder of TruLife Biotech.

In support of this initiative, the Company published a White Paper through Nutritional Outlook, an MJH Life Sciences brand that provides astute, well-informed insights and industry updates critical to manufacturers of dietary supplements, health foods and nutritious beverages.

Link to the publication: https://www.nutritionaloutlook.com/view/cbd-is-a-substance-with-poor-systemic-blood-exposure-one-scientist-explains-the-challenge-and-what-it-means

“Green Hygienics is poised to change the landscape of the industry and will continue the advancement of its hemp-derived cannabinoid phyto-remedy platform through TruLife Biotech, LLC.,” Dr. Darjania continued. “The company will serve as a biotechnology innovations hub for the GRYN portfolio companies, and ultimately the Company will secure a strategic advantage in the marketplace by introducing novel cannabinoids and targeted bio-delivery technologies to the formulations within its own brand portfolio.”

Dr. Darjania is a seasoned pharma-professional with over 20 years of experience in biotechnology and pharmaceutical drug research and development. He also held executive positions and led R&D projects at various cannabinoid-based enterprises.

About Green Hygienics Holdings Inc.
Green Hygienic Holdings Inc. (OTCQB: GRYN) (“Green Hygienics” or the “Company”) is a California-based innovative, technology-driven enterprise focused on the high standard cultivation and processing of industrial hemp and manufacturing of pharmaceutical-grade bioactive cannabinoids. The Company’s corporate mission is to adhere to the highest standards of operations in consistently delivering safe and premium-quality products to consumers as well as to partner with CPG (consumer packaged goods) and pharmaceutical companies.
Hygienics is the science of preserving and promoting the health of individuals, communities and the planet.

For further information about Green Hygienics Holdings Inc., please visit the Company’s website at: www.greenhygienics.com

Follow us on:

Facebook , Twitter and Linkedin


View our corporate video here .


Corporate Communications:
Heidi Thomasen
IR@GreenHygienics.com
Toll Free 1.855.802.0299

CAUTIONARY STATEMENT CONCERNING FORWARD-LOOKING STATEMENTS
This document contains forward-looking statements. In addition, from time to time, we or our representatives may make forward-looking statements orally or in writing. We base these forward-looking statements on our expectations and projections about future events, which we derive from the information currently available to us. Such forward-looking statements relate to future events or our future performance, including our financial performance and projections; our growth in revenue and earnings; and our business prospects and opportunities. You can identify forward-looking statements by those that are not historical in nature, particularly those that use terminology such as "may," "should," "expects," "anticipates," "contemplates," "estimates," "believes," "plans," "projected," "predicts," "potential," or "hopes" or the negative of these or similar terms. In evaluating these forward-looking statements, you should consider various factors, including our ability to change the direction of the Company; our ability to keep pace with new technology and changing market needs; and the competitive environment of our business. These and other factors may cause our actual results to differ materially from any forward-looking statement.

Public Relations:
InvestorBrandNetwork (IBN)
Los Angeles, California
www.InvestorBrandNetwork.com
310.299.1717 Office
Editor@InvestorBrandNetwork.com


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